A Convenient Route for Synthesis of 1,2,4-Triazolines as Substituents to Benzo[/]-4-hydroxy-152-dihydro-2- quinolone
نویسنده
چکیده
Benzo[/]-3-[(p-chlorophenylamino)(hydrazino)methyl]-4-hydroxy-1,2-dihydro-2-quinolone was prepared by the addition of H Br on — CH=N bond of the Schiff base followed by condensation with hydrazine and was used in the synthesis of different substituted triazolines borne on a quinolone moiety giving rise to a system of high probability to be of great biological importance. Some other derivatives of this class of compounds of expected pharmaceutical importance were obtained by the action of certain nucleophiles as well as by alkylation of the respective triazoline. The structures of the obtained compounds were elucidated by IR and H NMR spectroscopy.
منابع مشابه
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